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Systems pharmacology identifies drug targets for Stargardt disease–associated retinal degeneration

A systems pharmacological approach that capitalizes on the characterization of intracellular signaling networks can transform our understanding of human diseases and lead to therapy development. Here, we applied this strategy to identify pharmacological targets for the treatment of Stargardt disease...

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Dettagli Bibliografici
Autori principali: Chen, Yu, Palczewska, Grazyna, Mustafi, Debarshi, Golczak, Marcin, Dong, Zhiqian, Sawada, Osamu, Maeda, Tadao, Maeda, Akiko, Palczewski, Krzysztof
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859412/
https://ncbi.nlm.nih.gov/pubmed/24231350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69076
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