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Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice

Atrophic age-related and juvenile macular degeneration are especially devastating due to lack of an effective cure. Two retinal cell types, photoreceptor cells and the adjacent retinal pigmented epithelium (RPE), reportedly display the earliest pathological changes. Abca4(−/−)Rdh8(−/−) mice, which m...

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Detalhes bibliográficos
Main Authors: Maeda, Akiko, Palczewska, Grazyna, Golczak, Marcin, Kohno, Hideo, Dong, Zhiqian, Maeda, Tadao, Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986171/
https://ncbi.nlm.nih.gov/pubmed/24706832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317986111
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