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DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice

Photoreceptor cell death is the proximal cause of blindness in many retinal degenerative disorders; hence, understanding the gene regulatory networks that promote photoreceptor survival is at the forefront of efforts to combat blindness. Down-regulation of the microRNA (miRNA)-processing enzyme DICE...

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Detalhes bibliográficos
Main Authors: Sundermeier, Thomas R., Zhang, Ning, Vinberg, Frans, Mustafi, Debarshi, Kohno, Hideo, Golczak, Marcin, Bai, Xiaodong, Maeda, Akiko, Kefalov, Vladimir J., Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101655/
https://ncbi.nlm.nih.gov/pubmed/24812086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-254292
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