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Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice

Atrophic age-related and juvenile macular degeneration are especially devastating due to lack of an effective cure. Two retinal cell types, photoreceptor cells and the adjacent retinal pigmented epithelium (RPE), reportedly display the earliest pathological changes. Abca4(−/−)Rdh8(−/−) mice, which m...

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Hlavní autoři: Maeda, Akiko, Palczewska, Grazyna, Golczak, Marcin, Kohno, Hideo, Dong, Zhiqian, Maeda, Tadao, Palczewski, Krzysztof
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986171/
https://ncbi.nlm.nih.gov/pubmed/24706832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317986111
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