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Primary amines protect against retinal degeneration in mouse models of retinopathies

Vertebrate vision is initiated by photoisomerization of the visual pigment chromophore, 11-cis-retinal, and is maintained by continuous regeneration of this retinoid through a series of reactions termed the retinoid cycle. However, toxic side reaction products, especially those involving reactive al...

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Detalhes bibliográficos
Main Authors: Maeda, Akiko, Golczak, Marcin, Chen, Yu, Okano, Kiichiro, Kohno, Hideo, Shiose, Satomi, Ishikawa, Kaede, Harte, William, Palczewska, Grazyna, Maeda, Tadao, Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518042/
https://ncbi.nlm.nih.gov/pubmed/22198730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.759
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