Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration

Brain aging is associated with diminished circadian clock output and decreased expression of the core clock proteins, which regulate many aspects of cellular biochemistry and metabolism. The genes encoding clock proteins are expressed throughout the brain, though it is unknown whether these proteins...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Musiek, Erik S., Lim, Miranda M., Yang, Guangrui, Bauer, Adam Q., Qi, Laura, Lee, Yool, Roh, Jee Hoon, Ortiz-Gonzalez, Xilma, Dearborn, Joshua T., Culver, Joseph P., Herzog, Erik D., Hogenesch, John B., Wozniak, David F., Dikranian, Krikor, Giasson, Benoit I., Weaver, David R., Holtzman, David M., FitzGerald, Garret A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859381/
https://ncbi.nlm.nih.gov/pubmed/24270424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70317
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