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Regulation of amyloid-β dynamics and pathology by the circadian clock

Nighttime restlessness and daytime drowsiness are common and early symptoms of Alzheimer’s Disease (AD). This symptomology implicates dysfunctional biological timing, yet the role of the circadian system in AD pathogenesis is unknown. To evaluate the role of the circadian clock in amyloid-β (Aβ) dyn...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Kress, Geraldine J., Liao, Fan, Dimitry, Julie, Cedeno, Michelle R., FitzGerald, Garret A., Holtzman, David M., Musiek, Erik S.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881473/
https://ncbi.nlm.nih.gov/pubmed/29382695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20172347
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