DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements and chimaeric transcripts in mouse ES cells

DNA methylation and histone H3 lysine 9 trimethylation (H3K9me3) play important roles in silencing of genes and retroelements. However, a comprehensive comparison of genes and repetitive elements repressed by these pathways has not been reported. Here we show that in mouse embryonic stem cells (mESC...

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Detalhes bibliográficos
Main Authors: Karimi, Mohammad M., Goyal, Preeti, Maksakova, Irina A., Bilenky, Misha, Leung, Danny, Tang, Jie Xin, Shinkai, Yoichi, Mager, Dixie L., Jones, Steven, Hirst, Martin, Lorincz, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857791/
https://ncbi.nlm.nih.gov/pubmed/21624812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.04.004
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