H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing

BACKGROUND: Endogenous retroviruses (ERVs) are parasitic sequences whose derepression is associated with cancer and genomic instability. Many ERV families are silenced in mouse embryonic stem cells (mESCs) via SETDB1-deposited trimethylated lysine 9 of histone 3 (H3K9me3), but the mechanism of H3K9m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Maksakova, Irina A, Goyal, Preeti, Bullwinkel, Jörn, Brown, Jeremy P, Bilenky, Misha, Mager, Dixie L, Singh, Prim B, Lorincz, Matthew C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169442/
https://ncbi.nlm.nih.gov/pubmed/21774827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-4-12
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados