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A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells
In mouse embryonic stem cells (mESCs), the expression of provirus and endogenous retroelements is epigenetically repressed. Although many cellular factors involved in retroelement silencing have been identified, the complete molecular mechanism remains elusive. In this study, we performed a genome-w...
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| Vydáno v: | Genome Res |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5991520/ https://ncbi.nlm.nih.gov/pubmed/29728365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.227280.117 |
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