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Tim-3: An Activation Marker and Activation Limiter of Innate Immune Cells
Tim-3 was initially identified on activated Th1, Th17, and Tc1 cells and induces T cell death or exhaustion after binding to its ligand, Gal-9. The observed relationship between dysregulated Tim-3 expression on T cells and the progression of many clinical diseases has identified this molecule as an...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857553/ https://ncbi.nlm.nih.gov/pubmed/24339828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00449 |
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