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Tim-3: An Activation Marker and Activation Limiter of Innate Immune Cells

Tim-3 was initially identified on activated Th1, Th17, and Tc1 cells and induces T cell death or exhaustion after binding to its ligand, Gal-9. The observed relationship between dysregulated Tim-3 expression on T cells and the progression of many clinical diseases has identified this molecule as an...

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Detalhes bibliográficos
Main Authors: Han, Gencheng, Chen, Guojiang, Shen, Beifen, Li, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857553/
https://ncbi.nlm.nih.gov/pubmed/24339828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00449
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