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Tim-3 inhibits macrophage control of Listeria monocytogenes by inhibiting Nrf2
T cell immunoglobulin mucin-3 (Tim-3) is an immune checkpoint inhibitor and its dysregulation has been related to T cell tolerance and many immune disorders, such as tumors and infection tolerance. However, the physiopathology roles of Tim-3 in innate immunity remain elusive. Here, we demonstrate th...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5311873/ https://ncbi.nlm.nih.gov/pubmed/28205579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42095 |
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