Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors

The ex vivo sensitivity of pediatric leukemia cells to the proteasome inhibitor bortezomib was compared to 3 next generation proteasome inhibitors: the epoxyketone-based irreversible proteasome inhibitors carfilzomib, its orally bio-available analog ONX 0912, and the immunoproteasome inhibitor ONX 0...

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Bibliografiset tiedot
Päätekijät: Niewerth, Denise, Franke, Niels E., Jansen, Gerrit, Assaraf, Yehuda G., van Meerloo, Johan, Kirk, Christopher J., Degenhardt, Jeremiah, Anderl, Janet, Schimmer, Aaron D., Zweegman, Sonja, de Haas, Valerie, Horton, Terzah M., Kaspers, Gertjan J.L., Cloos, Jacqueline
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ferrata Storti Foundation 2013
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856965/
https://ncbi.nlm.nih.gov/pubmed/24056819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.092411
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