Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions

Pyrethroid insecticides are used to control diseases spread by arthropods. We have developed a suite of pyrethroid mimetic activity-based probes (PyABPs) to selectively label and identify P450s associated with pyrethroid metabolism. The probes were screened against pyrethroid-metabolizing and nonmet...

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Autors principals: Ismail, Hanafy M., O’Neill, Paul M., Hong, David W., Finn, Robert D., Henderson, Colin J., Wright, Aaron T., Cravatt, Benjamin F., Hemingway, Janet, Paine, Mark J. I.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856776/
https://ncbi.nlm.nih.gov/pubmed/24248381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320185110
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