New insecticide screening platforms indicate that Mitochondrial Complex I inhibitors are susceptible to cross-resistance by mosquito P450s that metabolise pyrethroids

Fenazaquin, pyridaben, tolfenpyrad and fenpyroximate are Complex I inhibitors offering a new mode of action for insecticidal malaria vector control. However, extended exposure to pyrethroid based products such as long-lasting insecticidal nets (LLINs) has created mosquito populations that are largel...

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Publicado no:Sci Rep
Main Authors: Lees, Rosemary S., Ismail, Hanafy M., Logan, Rhiannon A. E., Malone, David, Davies, Rachel, Anthousi, Amalia, Adolfi, Adriana, Lycett, Gareth J., Paine, Mark J. I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530702/
https://ncbi.nlm.nih.gov/pubmed/33004954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73267-x
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