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Determination of Androgen Receptor Degradation Enhancer ASC-J9(®) in Mouse Sera and Organs with Liquid Chromatography Tandem Mass Spectrometry

A novel androgen receptor (AR) degradation enhancer ASC-J9(®) has displayed beneficial effects during the in vitro and in vivo studies for treatment of prostate cancer, liver cancer, bladder cancer and spinal and bulbar muscular atrophy (SBMA). It works mainly by inducing the degradation of AR with...

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Autors principals: Soh, Shu Fang, Huang, Chiung-Kuei, Lee, Soo Ok, Xu, Defeng, Yeh, Shuyuan, Li, Jun, Yong, Eu Leong, Gong, Yinhan, Chang, Chawnshang
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856572/
https://ncbi.nlm.nih.gov/pubmed/24042123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2013.08.020
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