ASC-J9 Suppresses Castration-Resistant Prostate Cancer Growth through Degradation of Full-length and Splice Variant Androgen Receptors

Early studies suggested androgen receptor (AR) splice variants might contribute to the progression of prostate cancer (PCa) into castration resistance. However, the therapeutic strategy to target these AR splice variants still remains unresolved. Through tissue survey of tumors from the same patient...

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Главные авторы: Yamashita, Shinichi, Lai, Kuo-Pao, Chuang, Kun-Lung, Xu, Defeng, Miyamoto, Hiroshi, Tochigi, Tatsuo, Pang, See-Tong, Li, Lei, Arai, Yoichi, Kung, Hsing-Jien, Yeh, Shuyuan, Chang, Chawnshang
Формат: Artigo
Язык:Inglês
Опубликовано: Neoplasia Press Inc. 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281944/
https://ncbi.nlm.nih.gov/pubmed/22355276
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