ASC-J9 Suppresses Castration-Resistant Prostate Cancer Growth through Degradation of Full-length and Splice Variant Androgen Receptors

Early studies suggested androgen receptor (AR) splice variants might contribute to the progression of prostate cancer (PCa) into castration resistance. However, the therapeutic strategy to target these AR splice variants still remains unresolved. Through tissue survey of tumors from the same patient...

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Autori principali: Yamashita, Shinichi, Lai, Kuo-Pao, Chuang, Kun-Lung, Xu, Defeng, Miyamoto, Hiroshi, Tochigi, Tatsuo, Pang, See-Tong, Li, Lei, Arai, Yoichi, Kung, Hsing-Jien, Yeh, Shuyuan, Chang, Chawnshang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281944/
https://ncbi.nlm.nih.gov/pubmed/22355276
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