ASC-J9 Suppresses Castration-Resistant Prostate Cancer Growth through Degradation of Full-length and Splice Variant Androgen Receptors

Early studies suggested androgen receptor (AR) splice variants might contribute to the progression of prostate cancer (PCa) into castration resistance. However, the therapeutic strategy to target these AR splice variants still remains unresolved. Through tissue survey of tumors from the same patient...

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Detalhes bibliográficos
Main Authors: Yamashita, Shinichi, Lai, Kuo-Pao, Chuang, Kun-Lung, Xu, Defeng, Miyamoto, Hiroshi, Tochigi, Tatsuo, Pang, See-Tong, Li, Lei, Arai, Yoichi, Kung, Hsing-Jien, Yeh, Shuyuan, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281944/
https://ncbi.nlm.nih.gov/pubmed/22355276
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