Determination of Androgen Receptor Degradation Enhancer ASC-J9(®) in Mouse Sera and Organs with Liquid Chromatography Tandem Mass Spectrometry

A novel androgen receptor (AR) degradation enhancer ASC-J9(®) has displayed beneficial effects during the in vitro and in vivo studies for treatment of prostate cancer, liver cancer, bladder cancer and spinal and bulbar muscular atrophy (SBMA). It works mainly by inducing the degradation of AR with...

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Main Authors: Soh, Shu Fang, Huang, Chiung-Kuei, Lee, Soo Ok, Xu, Defeng, Yeh, Shuyuan, Li, Jun, Yong, Eu Leong, Gong, Yinhan, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856572/
https://ncbi.nlm.nih.gov/pubmed/24042123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2013.08.020
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