Determination of Androgen Receptor Degradation Enhancer ASC-J9(®) in Mouse Sera and Organs with Liquid Chromatography Tandem Mass Spectrometry

A novel androgen receptor (AR) degradation enhancer ASC-J9(®) has displayed beneficial effects during the in vitro and in vivo studies for treatment of prostate cancer, liver cancer, bladder cancer and spinal and bulbar muscular atrophy (SBMA). It works mainly by inducing the degradation of AR with...

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Bibliografiske detaljer
Main Authors: Soh, Shu Fang, Huang, Chiung-Kuei, Lee, Soo Ok, Xu, Defeng, Yeh, Shuyuan, Li, Jun, Yong, Eu Leong, Gong, Yinhan, Chang, Chawnshang
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856572/
https://ncbi.nlm.nih.gov/pubmed/24042123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2013.08.020
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