Anti-androgen therapy with Hydroxyflutamide or androgen receptor degradation enhancer ASC-J9(®) enhances BCG efficacy to better suppress bladder cancer progression

Recent studies suggested that the androgen receptor (AR) might play important roles to influence the bladder cancer (BCa) progression, yet its clinical application remains unclear. Here we developed a new combined therapy with Bacillus Calmette-Guérin (BCG) and the AR degradation enhancer ASC-J9(®)...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Shang, Zhiqun, Li, Yanjun, Zhang, Minghao, Tian, Jing, Han, Ruifa, Shyr, Chih-Rong, Messing, Edward, Yeh, Shuyuan, Niu, Yuanjie, Chang, Chawnshang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704455/
https://ncbi.nlm.nih.gov/pubmed/26264279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-1055-T
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