Anti-androgen therapy with Hydroxyflutamide or androgen receptor degradation enhancer ASC-J9(®) enhances BCG efficacy to better suppress bladder cancer progression

Recent studies suggested that the androgen receptor (AR) might play important roles to influence the bladder cancer (BCa) progression, yet its clinical application remains unclear. Here we developed a new combined therapy with Bacillus Calmette-Guérin (BCG) and the AR degradation enhancer ASC-J9(®)...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Shang, Zhiqun, Li, Yanjun, Zhang, Minghao, Tian, Jing, Han, Ruifa, Shyr, Chih-Rong, Messing, Edward, Yeh, Shuyuan, Niu, Yuanjie, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704455/
https://ncbi.nlm.nih.gov/pubmed/26264279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-1055-T
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