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Anti-androgen therapy with Hydroxyflutamide or androgen receptor degradation enhancer ASC-J9(®) enhances BCG efficacy to better suppress bladder cancer progression

Recent studies suggested that the androgen receptor (AR) might play important roles to influence the bladder cancer (BCa) progression, yet its clinical application remains unclear. Here we developed a new combined therapy with Bacillus Calmette-Guérin (BCG) and the AR degradation enhancer ASC-J9(®)...

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Dettagli Bibliografici
Pubblicato in:Mol Cancer Ther
Autori principali: Shang, Zhiqun, Li, Yanjun, Zhang, Minghao, Tian, Jing, Han, Ruifa, Shyr, Chih-Rong, Messing, Edward, Yeh, Shuyuan, Niu, Yuanjie, Chang, Chawnshang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704455/
https://ncbi.nlm.nih.gov/pubmed/26264279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-1055-T
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