Anti-androgen therapy with Hydroxyflutamide or androgen receptor degradation enhancer ASC-J9(®) enhances BCG efficacy to better suppress bladder cancer progression

Recent studies suggested that the androgen receptor (AR) might play important roles to influence the bladder cancer (BCa) progression, yet its clinical application remains unclear. Here we developed a new combined therapy with Bacillus Calmette-Guérin (BCG) and the AR degradation enhancer ASC-J9(®)...

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Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Shang, Zhiqun, Li, Yanjun, Zhang, Minghao, Tian, Jing, Han, Ruifa, Shyr, Chih-Rong, Messing, Edward, Yeh, Shuyuan, Niu, Yuanjie, Chang, Chawnshang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704455/
https://ncbi.nlm.nih.gov/pubmed/26264279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-1055-T
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