Deciphering the transcription complex critical for RhoA gene expression and cancer metastasis

RhoA GTPase plays a crucial role in numerous biological functions and is linked to cancer metastasis. However, the understanding of the molecular mechanism responsible for RhoA transcription is still very limited. Here we show that RhoA transcription is orchestrated by the Myc/Skp2/Miz1/p300 transcr...

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Bibliografiske detaljer
Main Authors: Chan, Chia-Hsin, Lee, Szu-Wei, Li, Chien-Feng, Wang, Jing, Yang, Wei-Lei, Wu, Ching-Yuan, Wu, Juan, Nakayama, Keiichi I., Kang, Hong-Yo, Huang, Hsuan-Ying, Hung, Mien-Chie, Pandolfi, Pier Paolo, Lin, Hui-Kuan
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855841/
https://ncbi.nlm.nih.gov/pubmed/20383141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2047
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