Deciphering the transcription complex critical for RhoA gene expression and cancer metastasis

RhoA GTPase plays a crucial role in numerous biological functions and is linked to cancer metastasis. However, the understanding of the molecular mechanism responsible for RhoA transcription is still very limited. Here we show that RhoA transcription is orchestrated by the Myc/Skp2/Miz1/p300 transcr...

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Hlavní autoři: Chan, Chia-Hsin, Lee, Szu-Wei, Li, Chien-Feng, Wang, Jing, Yang, Wei-Lei, Wu, Ching-Yuan, Wu, Juan, Nakayama, Keiichi I., Kang, Hong-Yo, Huang, Hsuan-Ying, Hung, Mien-Chie, Pandolfi, Pier Paolo, Lin, Hui-Kuan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855841/
https://ncbi.nlm.nih.gov/pubmed/20383141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2047
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