Doxorubicin Promotes Migration and Invasion of Breast Cancer Cells through the Upregulation of the RhoA/MLC Pathway

PURPOSE: Cancer cells develop acquired resistance induced by chemotherapeutic drugs. In this study, we investigated the effects of brief treatment with cytotoxic drugs on the phenotype of breast cancer cells. METHODS: Breast cancer cells MCF7 and BT-474 were briefly treated with paclitaxel or doxoru...

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Veröffentlicht in:J Breast Cancer
Hauptverfasser: Liu, Chien-Liang, Chen, Ming-Jen, Lin, Jiunn-Chang, Lin, Chi-Hsin, Huang, Wen-Chien, Cheng, Shih-Ping, Chen, Shan-Na, Chang, Yuan-Ching
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Breast Cancer Society 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597404/
https://ncbi.nlm.nih.gov/pubmed/31281722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4048/jbc.2019.22.e22
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