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Destruction of RhoA CULtivates actin

Cullin 3, the core subunit of the CRL3 ubiquitin ligase family, is essential for development, but its substrates remain poorly defined. Here, Chen et al. (2009) report that CRL3(BACURD) targets the RhoA GTPase for degradation thereby maintaining actin cytoskeleton integrity.

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wu, Shuangding, Wolf, Dieter A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981991/
https://ncbi.nlm.nih.gov/pubmed/19782022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.09.012
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