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The benzodiazepine diazepam potentiates responses of α1β2γ2 γ-aminobutyric acid type A receptors activated by either γ-aminobutyric acid or allosteric agonists

BACKGROUND: The γ-aminobutyric acid type A receptor is target for several anesthetics, anticonvulsants, anxiolytics and sedatives. Neurosteroids, barbiturates and etomidate both potentiate responses to γ-aminobutyric acid (GABA) and allosterically activate the receptor. We examined the ability of a...

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Hlavní autoři: Li, Ping, Eaton, Megan M., Steinbach, Joe Henry, Akk, Gustav
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852889/
https://ncbi.nlm.nih.gov/pubmed/23407108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318289bcd3
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