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γ-Aminobutyric Acid Type A α4, β2, and δ Subunits Assemble to Produce More Than One Functionally Distinct Receptor Type

Native γ-aminobutyric acid (GABA)(A) receptors consisting of α4, β1–3, and δ subunits mediate responses to the low, tonic concentration of GABA present in the extracellular milieu. Previous studies on heterologously expressed α4βδ receptors have shown a large degree of variability in functional prop...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Eaton, Megan M., Bracamontes, John, Shu, Hong-Jin, Li, Ping, Mennerick, Steven, Steinbach, Joe Henry, Akk, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244592/
https://ncbi.nlm.nih.gov/pubmed/25238745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.094813
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