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γ-Aminobutyric Acid Type A α4, β2, and δ Subunits Assemble to Produce More Than One Functionally Distinct Receptor Type

Native γ-aminobutyric acid (GABA)(A) receptors consisting of α4, β1–3, and δ subunits mediate responses to the low, tonic concentration of GABA present in the extracellular milieu. Previous studies on heterologously expressed α4βδ receptors have shown a large degree of variability in functional prop...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Pharmacol
Prif Awduron: Eaton, Megan M., Bracamontes, John, Shu, Hong-Jin, Li, Ping, Mennerick, Steven, Steinbach, Joe Henry, Akk, Gustav
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244592/
https://ncbi.nlm.nih.gov/pubmed/25238745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.094813
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