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The role of structural and energetic factors in regulating repair of a bulky DNA lesion with different opposite partner bases()
Extensive molecular modeling with molecular dynamics simulations and van der Waals energy analyses were used to elucidate the striking finding that a mutagenic benzo[a]pyrene-derived DNA lesion, the base-displaced intercalated 10R-(+)-cis-anti-B[a]P-N(2)-dG (G*), manifests large differences in nucle...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3850756/ https://ncbi.nlm.nih.gov/pubmed/23902560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4009177 |
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