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Determination of the pharmacokinetics of glycopyrronium in the lung using a population pharmacokinetic modelling approach

AIMS: Glycopyrronium bromide (NVA237) is a once-daily long-acting muscarinic antagonist recently approved for the treatment of chronic obstructive pulmonary disease. In this study, we used population pharmacokinetic (PK) modelling to provide insights into the impact of the lung PK of glycopyrronium...

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Autors principals: Bartels, Christian, Looby, Michael, Sechaud, Romain, Kaiser, Guenther
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845310/
https://ncbi.nlm.nih.gov/pubmed/23506208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12118
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