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Determination of the pharmacokinetics of glycopyrronium in the lung using a population pharmacokinetic modelling approach

AIMS: Glycopyrronium bromide (NVA237) is a once-daily long-acting muscarinic antagonist recently approved for the treatment of chronic obstructive pulmonary disease. In this study, we used population pharmacokinetic (PK) modelling to provide insights into the impact of the lung PK of glycopyrronium...

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書目詳細資料
Main Authors: Bartels, Christian, Looby, Michael, Sechaud, Romain, Kaiser, Guenther
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845310/
https://ncbi.nlm.nih.gov/pubmed/23506208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12118
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