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An Approach for Identifiability of Population Pharmacokinetic–Pharmacodynamic Models

Mathematical models are routinely used in clinical pharmacology to study the pharmacokinetic and pharmacodynamic properties of a drug in the body. Identifiability of these models is an important requirement for the success of these clinical studies. Identifiability is classified into two types, stru...

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Библиографические подробности
Главные авторы: Shivva, V, Korell, J, Tucker, I G, Duffull, S B
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697038/
https://ncbi.nlm.nih.gov/pubmed/23887745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2013.25
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