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The Population Pharmacokinetics of d-β-hydroxybutyrate Following Administration of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate

The administration of ketones to induce a mild ketosis is of interest for the alleviation of symptoms associated with various neurological disorders. This study aimed to understand the pharmacokinetics (PK) of d-β-hydroxybutyrate (BHB) and quantify the sources of variability following a dose of (R)-...

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Bibliografske podrobnosti
izdano v:AAPS J
Main Authors: Shivva, Vittal, Cox, Pete J., Clarke, Kieran, Veech, Richard L., Tucker, Ian G., Duffull, Stephen B.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256599/
https://ncbi.nlm.nih.gov/pubmed/26893218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-016-9879-0
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