Oral 28-day and developmental toxicity studies of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate

(R)-3-Hydroxybutyl (R)-3-hydroxybutyrate (ketone monoester) has been developed as an oral source of ketones, which may be utilized for energy. In a 28-day toxicity study, Crl:WI (Wistar) rats received diets containing, as 30% of the calories, ketone monoester (12 and 15 g/kg body weight/day for male...

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Detalhes bibliográficos
Main Authors: Clarke, Kieran, Tchabanenko, Kirill, Pawlosky, Robert, Carter, Emma, Knight, Nicholas S., Murray, Andrew J., Cochlin, Lowri E., King, M. Todd, Wong, Andrea W., Roberts, Ashley, Robertson, Jeremy, Veech, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809901/
https://ncbi.nlm.nih.gov/pubmed/22504461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yrtph.2012.04.001
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