Determination of the pharmacokinetics of glycopyrronium in the lung using a population pharmacokinetic modelling approach

AIMS: Glycopyrronium bromide (NVA237) is a once-daily long-acting muscarinic antagonist recently approved for the treatment of chronic obstructive pulmonary disease. In this study, we used population pharmacokinetic (PK) modelling to provide insights into the impact of the lung PK of glycopyrronium...

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Bibliografske podrobnosti
Main Authors: Bartels, Christian, Looby, Michael, Sechaud, Romain, Kaiser, Guenther
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2013
Teme:
Pharmacokinetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845310/
https://ncbi.nlm.nih.gov/pubmed/23506208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12118
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