Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and histologic characteristics of human cancers

BACKGROUND: The patient-derived xenograft (PDX) model is likely to reflect human tumor biology more accurately than cultured cell lines because human tumors are implanted directly into animals; maintained in an in vivo, three-dimensional environment; and never cultured on plastic. PDX models of head...

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Hlavní autoři: Peng, Shaohua, Creighton, Chad J, Zhang, Yiqun, Sen, Banibrata, Mazumdar, Tuhina, Myers, Jeffery N, Woolfson, Adrian, Lorenzi, Matthew V, Bell, Diana, Williams, Michelle D, Johnson, Faye M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844397/
https://ncbi.nlm.nih.gov/pubmed/23981300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-198
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