Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and histologic characteristics of human cancers

BACKGROUND: The patient-derived xenograft (PDX) model is likely to reflect human tumor biology more accurately than cultured cell lines because human tumors are implanted directly into animals; maintained in an in vivo, three-dimensional environment; and never cultured on plastic. PDX models of head...

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Detalhes bibliográficos
Main Authors: Peng, Shaohua, Creighton, Chad J, Zhang, Yiqun, Sen, Banibrata, Mazumdar, Tuhina, Myers, Jeffery N, Woolfson, Adrian, Lorenzi, Matthew V, Bell, Diana, Williams, Michelle D, Johnson, Faye M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844397/
https://ncbi.nlm.nih.gov/pubmed/23981300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-198
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