Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors

The genomic alterations identified in head and neck squamous cell carcinoma (HNSCC) tumors have not resulted in any changes in clinical care, making the development of biomarker-driven targeted therapy for HNSCC a major translational gap in knowledge. To fill this gap, we used 59 molecularly charact...

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Bibliographic Details
Published in:Cancer Lett
Main Authors: Zhang, Ming, Singh, Ratnakar, Peng, Shaohua, Mazumdar, Tuhina, Sambandam, Vaishnavi, Shen, Li, Tong, Pan, Li, Lerong, Kalu, Nene, Pickering, Curtis R., Frederick, Mitchell, Myers, Jeffrey N., Wang, Jing, Johnson, Faye M.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404895/
https://ncbi.nlm.nih.gov/pubmed/28126323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.01.024
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