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STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma

PURPOSE: The inhibition of c-Src results in a striking reduction in cancer cell invasion, but the effect on cell survival is modest. Defining mechanisms that limit apoptosis following c-Src inhibition could result in an ideal therapeutic approach that both inhibits invasion and leads to apoptosis. I...

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Detaylı Bibliyografya
Asıl Yazarlar: Sen, Banibrata, Peng, Shaohua, Woods, Denise M., Wistuba, Ignacio, Bell, Diana, El-Nagar, Adel, Lai, Stephen Y., Johnson, Faye M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251692/
https://ncbi.nlm.nih.gov/pubmed/22090359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1889
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