Inhibition of JAK2/STAT3/SOCS3 signaling attenuates atherosclerosis in rabbit

Abstract Background Previous studies have indicated that the JAK/STAT signaling pathway is involved in modulating arterial adventitia inflammation response. In this study, we designed experiments to further investigate the effect of JAK2/STAT3/SOCS3 signaling in rabbit atherosclerosis process. Metho...

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Detalhes bibliográficos
Main Authors: Xilan Yang, Jian Jia, Zhen Yu, Zheng Duanmu, Huiwei He, Sen Chen, Chen Qu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-03-01
Colecção:BMC Cardiovascular Disorders
Assuntos:
JAK2/STAT3/SOCS3 signaling pathway
Atherosclerosis
Ruxolitinib
Acesso em linha:http://link.springer.com/article/10.1186/s12872-020-01391-7
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