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Distinct interactions between c-Src and c-Met in mediating resistance to c-Src inhibition in head and neck cancer

PURPOSE: c-Src inhibition in cancer cells leads to an abrogation of invasion but a variable effect on apoptosis. The pathways downstream of c-Src promoting survival are not well-characterized. Because cancer therapy that both decreases invasion and induces significant apoptosis would be ideal, we so...

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Hlavní autoři: Sen, Banibrata, Peng, Shaohua, Saigal, Babita, Williams, Michelle D., Johnson, Faye M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460647/
https://ncbi.nlm.nih.gov/pubmed/21106725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1617
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