EFFECT OF HUMAN 15-LIPOXYGENASE-1 METABOLITES ON VASCULAR FUNCTION IN MOUSE MESENTERIC ARTERIES AND HEARTS

Lipoxygenases regulate vascular function by metabolizing arachidonic acid (AA) to dilator eicosanoids. Previously, we showed that endothelium-targeted adenoviral vector-mediated gene transfer of the human 15-lipoxygenase-1 (h15-LO-1) enhances arterial relaxation through the production of vasodilator...

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Autori principali: Kriska, Tamas, Cepura, Cody, Siangjong, Lawan, Wan, Tina C., Auchampach, John A., Shaish, Aviv, Haratz, Dror, Kumar, Ganesh, Falck, John R., Gauthier, Kathryn M., Campbell, William B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844054/
https://ncbi.nlm.nih.gov/pubmed/23872364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2013.07.002
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