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Role of macrophage PPARγ in experimental hypertension

Targeted disruption of the Alox15 gene makes mice resistant to angiotensin II-, DOCA/salt-, and N(ω)-nitro-l-arginine methyl ester (l-NAME)-induced experimental hypertension. Macrophages, a primary source of Alox15, are facilitating this resistance, but the underlying mechanism is not known. Because...

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Main Authors: Kriska, Tamas, Cepura, Cody, Gauthier, Kathryn M., Campbell, William B.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920151/
https://ncbi.nlm.nih.gov/pubmed/24163073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00287.2013
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