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15-Lipoxygenase metabolites contribute to age-related reduction in acetylcholine-induced hypotension in rabbits

Arachidonic acid (AA) metabolites from the 15-lipoxygenase-1 (15-LO-1) pathway, trihydroxyeicosatrienoic acids (THETAs) and hydroxy-epoxyeicosatrienoic acids (HEETAs), are endothelium-derived hyperpolarizing factors (EDHFs) and relax rabbit arteries. Rabbit vascular 15-LO-1 expression, THETA and HEE...

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Detalhes bibliográficos
Main Authors: Aggarwal, Nitin T., Gauthier, Kathryn M., Campbell, William B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494760/
https://ncbi.nlm.nih.gov/pubmed/18456739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00054.2008
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