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Chronic hypoxia enhances 15-lipoxygenase-mediated vasorelaxation in rabbit arteries
15-Lipoxygenase (15-LO-1) metabolizes arachidonic acid (AA) to 11,12,15-trihydroxyeicosatrienoic acids (THETAs) and 15-hydroxy-11,12-epoxyeicosatrienoic acids (HEETA) that dilate rabbit arteries. Increased endothelial 15-LO-1 expression enhances arterial relaxations to agonists. We tested the effect...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660232/ https://ncbi.nlm.nih.gov/pubmed/19112096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00777.2008 |
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