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Endothelial Nitric Oxide and 15-Lipoxygenase-1 Metabolites Independently Mediate Relaxation of the Rabbit Aorta

Endothelial 15-lipoxygenase-1 (15-LO-1) metabolites of arachidonic acid (AA), 11,12,15-trihydroxyeicosatrienoic acid (THETA) and 15-hydroxy-11,12-epoxyeicosatrienoic acid (HEETA) and nitric oxide (NO) mediate relaxations to acetylcholine (ACH). However, interactions between NO and the 15-LO-1 pathwa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aggarwal, Nitin T., Gauthier, Kathryn M., Campbell, William B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268834/
https://ncbi.nlm.nih.gov/pubmed/22197897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2011.12.002
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