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Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell–mediated cytotoxicity
Natural killer (NK) lymphocytes contain lysosome-related organelles (LROs), known as lytic granules, which upon formation of immune synapse with the target cell, polarize toward the immune synapse to deliver their contents to the target cell membrane. Here, we identify a small GTP-binding protein, A...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Cell Biology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842998/ https://ncbi.nlm.nih.gov/pubmed/24088571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-05-0259 |
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